Handbook of COVID-19 Prevention and Treatment

In order to win this inevitable battle and fight against COVID-19, we must work together and share our experiences around the world. The First Affiliated Hospital, Zhejiang University School of Medicine has treated 104 patients with confirmed COVID-19 in the past 50 days, and their experts wrote real treatment experience night and day, and quickly published this Handbook of COVID-19 Prevention and Treatment, expecting to share their invaluable practical advice and references with medical staff around the world. This handbook compared and analyzed the experience of other experts in China, and provides good reference to key departments such as hospital infection management, nursing, and outpatient clinics. This handbook provides comprehensive guidelines and best practices by China’s top experts for coping with COVID-19.

This handbook, provided by the First Affiliated Hospital of Zhejiang University, describes how organizations can minimize the cost while maximizing the effect of measures to manage and control the coronavirus outbreak. The handbook also discusses why hospitals and other healthcare institutions should have command centers when encountering a large-scale emergency in the context of COVID-19. This handbook also includes the following：

Technical strategies for addressing issues during emergencies.

Treatment methods to treat the critically ill.

Efficient clinical decision-making support.

Best practices for key departments like inflection management and outpatient clinics.

Editor’s Note:

Faced with an unknown virus, sharing and collaboration are the best remedy. The publication of this Handbook is one of the best ways to mark the courage and wisdom our healthcare workers have demonstrated over the past two months. Thanks to all those who have contributed to this Handbook, sharing the invaluable experience with healthcare colleagues around the world while saving the lives of patients. Thanks to the support from healthcare colleagues in China who have provided experience that inspires and motivates us. Thanks to Jack Ma Foundation for initiating this program, and to AliHealth for the technical support, making this Handbook possible to support the fight against the epidemic. The Handbook is available to everyone for free. However, due to the limited time, there might be some errors and defects. Your feedback and advice are highly welcomed!

Prof. Tingbo LIANG

Editor-in-Chief of the Handbook of COVID-19 Prevention and Treatment

Chairman of The First Affiliated Hospital, Zhejiang University School of Medicine

Contents
Part One Prevention and Control Management
I. Isolation Area Management…………………………………………………………………………………………,
II. Staff Management………………………………………………………………………………………………….. .4
Ill. COVID-19 Related Personal Protection Management…………………………………………………….5
IV. Hospital Practice Protocols during COVID-19 Epidemic…………………………………………………..6
V. Digital Support for Epidemic Prevention and Control. …………………………………………………….16
Part Two Diagnosis and Treatment
I. Personalized, Collaborative and Multidisciplinary Management………………………………………18
II.Etiology and Inflammation lndicators………………………………………………………………………….19
Ill. Imaging Findings of COVID-19 Patients……………………………………………………………………..21
IV. Application of Bronchoscopy in the Diagnosis and Management of COVID-19 Patients……..22
V. Diagnosis and Clinical Classification of COVID-19…………………………………………………………22
VI. Antiviral Treatment for Timely Elimination of Pathogens………………………………………………23
VII. Anti-shock and Anti-hypoxemia Treatment………………………………………………………………..24
VIII. The Rational Use of Antibiotics to Prevent Secondary lnfection…………………………………….29
IX. The Balance of Intestinal Microecology and Nutritional Support…………………………………….30
X. ECMO Support for COVID-19 Patients………………………………………………………………………….32
XI. Convalescent Plasma Therapy for COVID-19 Patients……………………………………………………35
XII. TCM Classification Therapy to Improve Curative Efficacy……………………………………………….36
XIII. Drug Use Management of COVID-19 Patients…………………………………………………………….37
XIV. Psychological Intervention for COVID-19 Patients……………………………………………………….41
XV. Rehabilitation Therapy for COVID-19 Patients……………………………………………………………..42
XVI. Lung Transplantation in Patients with COVID- l 9………………………………………………………..44
XVII. Discharge Standards and Follow-up Plan for COVID-19 Patients………………………………….45
Part Three Nursing
I. Nursing Care for Patients Receiving High-Flow Nasal Cannula {HFNC) Oxygen Therapy……….47
II. Nursing Care in Patients with Mechanical Ventilation…………………………………………………….47
Ill. Daily Management and Monitoring of ECMO {Extra Corporeal Membrane Oxygenation)…….49
IV. Nursing Care of ALSS {Artificial Liver Support System)…………………………………………………..50
V. Continuous Renal Replacement Treatment {CRRT) Care………………………………………………….51
VI. General Care………………………………………………………………………………………………………….52
Appendix
I. Medical Advice Example for COVID-19 Patients……………………………………………………………..53
II. Online Consultation Process for Diagosis and Treatment……………………………………………….57
References………………………………………………………………………………………………………………………………..59